Given its favorable reproductive safety profile, lamotrigine is a reasonable option for women who require treatment with a mood stabilizer during pregnancy.
Does lamotrigine cause birth defects?
A study published last year in the journal Neurology also found that babies born to pregnant women taking lamotrigine appeared not be at an increased risk of birth defects, such as cleft lip, cleft palate or clubfoot.
What pregnancy category is lamotrigine?
Safety of Psychiatric Medications During Pregnancy and Lactation
|Drug||FDA pregnancy category*|
|Valproic acid (Depakene)||D|
Can lamotrigine cause a miscarriage?
There is currently no proof that lamotrigine use in pregnancy causes miscarriage or stillbirth.
Does lamotrigine cross the placenta?
Lamotrigine has a good tolerability and safety profile, but is known to cross the placenta. There is no consensus regarding its use in pregnancy.
What is the safest antidepressant for pregnancy?
Antidepressants that are considered safer include:
- Fluoxetine (Prozac, Sarafem)
- Citalopram (Celexa)
- Sertraline (Zoloft)
- Amitriptyline (Elavil)
- Desipramine (Norpramin)
- Nortriptyline (Pamelor)
- Bupropion (Wellbutrin)
Does Lamictal deplete folic acid?
Anticonvulsants that do not induce cytochrome P450 enzymes, such as lamotrigine (Lamictal), are not associated with low levels of folic acid.
Can you take anti anxiety meds while pregnant?
Generally, these antidepressants are an option during pregnancy: Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft). Potential complications include maternal weight changes and premature birth.
What is Category D in pregnancy?
Category D. There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease in which safer drugs cannot be used or are ineffective).
What happens if you stop taking lamotrigine?
If you suddenly stop taking lamotrigine, you may experience seizures. If you do stop taking lamotrigine for any reason, do not start taking it again without talking to your doctor.
How safe is lamotrigine?
Lamotrigine (Lamictal) has been associated with a rare, but serious and life-threatening adverse reaction called hemophagocytic lymphohistiocytosis (HLH), which can lead to multi-organ failure resulting in hospitalization or death, particularly if diagnosis and treatment are delayed.
Can pregnancy make bipolar worse?
And the factors that lead to relapse during pregnancy are not clear. Bipolar disorder, however, can worsen during pregnancy. Pregnant women or new mothers with bipolar disorder have seven times the risk of hospital admissions compared to pregnant women who do not have bipolar disorder.